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Because of their research, Theodent now knows that pregnant women should not consume caffeine because caffeine can block the skeletal development of growing babies. As research projects have increased, various molecules of caffeine have been studied, namely theophylline (found in tea) and theobromine (found in chocolate). The initial hypothesis is that all members of this molecular family, called methylxanthine, have similar effects and are detrimental to the development of teeth and bones. In the 1990s, Theodent collaborated with Alexander Falster and Dr. William Simmons of the Department of Geology and Geophysics at the University of New Orleans and found that although caffeine does reduce the size of the enamel crystals, theobromine has the opposite effect. To reaffirm this, they found that under the action of theobromine, the size of the enamel crystals increased, rather than the expected effect of theobromine on the enamel crystals.