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Nuphoria, founded by Drs. Valerie Monteiro, D. C, and John Coppola, D. C, became dissatisfied with the standard medical care provided to patients with peripheral neuropathy. Nuphoria cause of neuropathy is unknown, and once you have neuropathy it is permanent, patients with neuropathy are told. It only requires that you learn to accept it. To make matters worse, patients with neuropathy are receiving a variety of medications to alleviate their pain, including NORCO® (hydrocodone bitartrate and acetaminophen), Neurontin® (gabapentin), Lyrica® (pregabalin), Cymbalta® (duloxetine hydrochloride), and others. The fact that the medications do not heal the nerves is the drawback of this strategy. They merely mask the pain, worsening the neuropathy at the same time. However, the real issue begins with all of the medication-related side effects. The side effects can sometimes be just as bad as the neuropathy itself.